Key Papers
- Buck L, Axel R (April 1991). "A novel multigene family may encode odorant receptors: a molecular basis for odor recognition". Cell 65 (1): 175–87. doi:10.1016/0092-8674(91)90418-X. PMID 1840504. This is the paper in which Linda B. Buck and Axel first describe the discovery of the odorant receptors, which was the basis for their shared Nobel Prize.
- Pellicer A, Wigler M, Axel R, Silverstein S (May 1978). "The transfer and stable integration of the HSV thymidine kinase gene into mouse cells". Cell 14 (1): 133–41. doi:10.1016/0092-8674(78)90308-2. PMID 208776.
- Pellicer A, Robins D, Wold B, et al. (September 1980). "Altering genotype and phenotype by DNA-mediated gene transfer". Science 209 (4463): 1414–22. doi:10.1126/science.7414320. PMID 7414320.
These are the papers describing DNA transfection, a critical tool for the entire revolution in biology, in which genes can be modified and then stably transferred into cells. This paper was the basis for the "Axel patent" which at one time brought Columbia University as much as $100 million per year.
Read more about this topic: Richard Axel
Famous quotes containing the words key and/or papers:
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—Bible: New Testament, Luke 11:52.
“I see by the papers that you have once more stirred that pool of intellectual stagnation, the educational convention.”
—Elizabeth Cady Stanton (1815–1902)