Ribose-5-phosphate Isomerase

Ribose-5-phosphate isomerase (Rpi) is an enzyme that catalyzes the conversion between ribose-5-phosphate (R5P) and ribulose-5-phosphate (Ru5P). It is a member or a larger class of isomerases which catalyze the interconversion of chemical isomers (in this case structural isomers of pentose). It plays a vital role in biochemical metabolism in both the pentose phosphate pathway and the Calvin cycle. The systematic name of this enzyme class is D-ribose-5-phosphate aldose-ketose-isomerase.

Read more about Ribose-5-phosphate IsomeraseStructure, Mechanism, Protein Genetics, Rpi Deficiency, RpiA and The Malaria Parasite, Structural Studies