Rhodope may mean:
- Queen Rhodope, a figure of Greek mythology
- Rhodope Mountains, in Bulgaria and Greece
- Rhodope (regional unit), of Greece
- Rhodope (Roman province), a late Roman and early Byzantine province
- 166 Rhodope, an asteroid
- Rhodope (gastropod), a genus of the family Rhodopidae, order Rhodopemorpha, class Gastropoda
- Mylothris rhodope, a Dotted Border butterfly endemic to tropical Africa commonly known as the Rhodope