Mitosis
Yet another major aspect of cellular behavior that is thought to include rho protein signaling is the process of cell division, mitosis. While it was thought for years that rho GTPase activity is restricted only to actin polymerization and therefore only to cytokinesis, new evidence that shows some activity in microtubule formation and the overall process of mitosis has arisen. This topic is still debated, and there is evidence both for and against for the importance of rho in mitosis.
Read more about this topic: Rho Family Of GTPases, Functions