The Rho family of GTPases is a family of small (~21 kDa) signaling G protein (more specific, a GTPase), and is a subfamily of the Ras superfamily. The members of the Rho GTPase family have been shown to regulate many aspects of intracellular actin dynamics, and are found in all eukaryotic organisms including yeasts and some plants. Three members of the family have been studied a great deal: Cdc42, Rac1, and RhoA. Rho proteins have been described as "molecular switches" and play a role in cell proliferation, apoptosis, gene expression, and multiple other common cellular functions.
Read more about Rho Family Of GTPases: History, Categorization, Regulators, Effectors, Functions
Famous quotes containing the word family:
“Family lore can be a bore, but only when you are hearing it, never when you are relating it to the ones who will be carrying it on for you. A family without a storyteller or two has no way to make sense out of their past and no way to get a sense of themselves.”
—Frank Pittman (20th century)