RGS6

RGS6

Identifiers Symbols RGS6; GAP External IDs OMIM: 603894 MGI: 1354730 HomoloGene: 68385 GeneCards: RGS6 Gene

Gene Ontology
Molecular function	• signal transducer activity • GTPase activator activity • protein binding
Cellular component	• cytoplasm • heterotrimeric G-protein complex • plasma membrane
Biological process	• G-protein coupled receptor signaling pathway • regulation of G-protein coupled receptor protein signaling pathway • intracellular signal transduction • termination of G-protein coupled receptor signaling pathway • positive regulation of GTPase activity • positive regulation of neuron differentiation
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 9628 50779 Ensembl ENSG00000182732 ENSMUSG00000021219 UniProt P49758 Q9Z2H2 RefSeq (mRNA) NM_001204416 NM_015812 RefSeq (protein) NP_001191345 NP_056627 Location (UCSC) Chr 14:
72.4 – 73.03 Mb Chr 12:
82.62 – 83.13 Mb PubMed search

Regulator of G-protein signaling 6 is a protein that in humans is encoded by the RGS6 gene.

Members of the RGS (regulator of G protein signaling) family have been shown to modulate the functioning of G proteins by activating the intrinsic GTPase activity of the alpha (guanine nucleotide-binding) subunits.