RGS5

RGS5

Identifiers Symbols RGS5; MST092; MST106; MST129; MSTP032; MSTP092; MSTP106; MSTP129 External IDs OMIM: 603276 MGI: 1098434 HomoloGene: 2682 GeneCards: RGS5 Gene

Gene Ontology
Molecular function	• GTPase activator activity
Cellular component	• cytoplasm • plasma membrane
Biological process	• signal transduction • regulation of G-protein coupled receptor protein signaling pathway • termination of G-protein coupled receptor signaling pathway • positive regulation of GTPase activity
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 8490 19737 Ensembl ENSG00000143248 ENSMUSG00000026678 UniProt O15539 O08850 RefSeq (mRNA) NM_001195303 NM_009063 RefSeq (protein) NP_001182232 NP_033089 Location (UCSC) Chr 1:
163.08 – 163.19 Mb Chr 1:
169.66 – 169.7 Mb PubMed search

Regulator of G-protein signaling 5 is a protein that in humans is encoded by the RGS5 gene.

The regulator of G protein signaling (RGS) proteins are signal transduction molecules that have structural homology to SST2 of Saccharomyces cerevisiae and EGL-10 of Caenorhabditis elegans. Multiple genes homologous to SST2 are present in higher eukaryotes. RGS proteins are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators.