Other Developments Because of Reverse Vaccinology and Bioinformatics
- Reverse vaccinology has caused an increased focus on pathogenic biology.
- Reverse vaccinology led to the discovery of pili in gram-positive pathogens such as A streptococcus, B streptococcus, and pneumococcus. Previously, all gram-positive bacteria were thought to not have any pili.
- Reverse vaccinology also led to the discovery of factor G binding protein in meningococcus, which binds to complement factor H in humans. Binding to the complement factor H allows for meningococcus to grow in human blood while blocking alternative pathways. This model does not fit many animal species, which do not have the same complement factor H as humans, indicating differentiation of meningococcus between differeing species.
Read more about this topic: Reverse Vaccinology
Famous quotes containing the words developments and/or reverse:
“I don’t wanna live in a city where the only cultural advantage is that you can make a right turn on a red light.
Freedom from labor itself is not new; it once belonged among the most firmly established privileges of the few. In this instance, it seems as though scientific progress and technical developments had been only taken advantage of to achieve something about which all former ages dreamed but which none had been able to realize.”
—Hannah Arendt (1906–1975)
“Now listen, buddy, there are a few corny ideas you got to get out of your head if you’re going to fly an airplane. Most things are just the reverse from what people think. The higher you are the safer you are. The Earth down there, that, that’s your enemy because once you hit that, boy, you splatter.”
—Dalton Trumbo (1905–1976)