Reverse triiodothyronine (3,3',5'-Triiodothyronine, reverse T3, or rT3) is a molecule that is an isomer of triiodothyronine (T3). Like T3, it is derived from thyroxine (T4).
rT3 increases in conditions such as sick euthyroid syndrome. rT3 is an inactive form of thyroid hormone. It increases in sick euthyroid syndrome because its clearance decreases while its production stays the same. The decreased clearance is possibly from lower 5'-deiodinase activity in the peripheral tissue or decreased liver uptake of rT3.
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Famous quotes containing the word reverse:
“They shall beat their swords into plowshares, and their spears into pruninghooks: nation shall not lift up sword against nation, neither shall they learn war any more.”
—Bible: Hebrew Isaiah, 2:4.
The words reappear in Micah 4:3, and the reverse injunction is made in Joel 3:10 (”Beat your plowshares into swords ...”)