Ras in Cancer
Mutations in the Ras family of proto-oncogenes (comprising H-Ras, N-Ras and K-Ras) are very common, being found in 20% to 30% of all human tumours. it is reasonable to speculate that a pharmacological approach that curtails Ras activity may represent a possible method to inhibit certain cancer types. Ras point mutations are the single most common abnormality of human proto-oncogenes. Ras inhibitor trans-farnesylthiosalicylic acid (FTS, Salirasib) exhibits profound anti-oncogenic effects in many cancer cell lines.
Read more about this topic: Ras Subfamily
Famous quotes containing the word cancer:
“Ever since I was a kid my folks fed me bigotry for breakfast and ignorance for supper. Never, not once did they ever make me feel proud of where I was born. That’s it. That was a cancer they put in me. No knowledge of my country. No pride. Just a hymn of hate.”
—Samuel Fuller (b. 1911)