Other
- R-2 (missile), an improved version of German V-2 rocket manufactured by the Soviet Union
- R2 signalling, a family of telephony protocols for line and register signalling
- BBC Radio 2, a British radio station
- DVD region code 2
- Region 2, the DVD region code for Europe (except Russia, Ukraine, and Belarus), Middle East, Egypt, Japan, South Africa, Swaziland, Lesotho, Greenland
- Gangrene ICD-10 code
- A version of NASA's Robonaut
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