Pyro comes from the Greek word πυρ (pyr) meaning fire. In English, it can be a prefix pertaining to fire, or it may refer to:
- Fire
- Fire, the rapid oxidation of a material in the chemical process of combustion, releasing heat, light, and various reaction products. Slower oxidative processes like rusting or digestion are not included by this definition.
- Pyrotechnics, the science of using materials capable of undergoing exothermic chemical reactions for the production of heat, light, gas, smoke and/or sound
- Pyrotechnician
- Pyrotechnic fastener, also known as pyros or explosive bolts
- Pyromaniac, someone with a mental illness that wills them to start fires.
In computing and computer games:
- Pyro Studios, a computer game developer based in Madrid
- PYthon Remote Objects, a remote procedure call library for the Python programming language
- Python Robotics, a project designed to create an easy-to-use interface for accessing and controlling a wide variety of real and simulated robots
- The Pyro, a playable class in the Team Fortress and Team Fortress 2 games
- Pyro 2, an ASCII game
- Pyro, a god in Sacrifice (video game)
In entertainment:
- Pyro (Transformers), a fictional character
- Pyro (comics), a fictional fire-controlling mutant in Marvel Comics's X-Men titles
- Fuego (1964 film), also known as Pyro, a suspense film starring Martha Hyer and Barry Sullivan
- "Pyro" (song), second single from Kings of Leon's 2010 album Come Around Sundown
- The Pyro, a playable character in the 2007 video game, Team Fortress 2.
- Mick Pyro, born Michael Tierney, Irish musician and journalist
In military issues:
- USS Pyro, the name of two U.S. Navy ammunition ships
- Pyros (bomb), a small guided bomb developed for use by unmanned aerial vehicles
Other uses:
- Pyro (horse), American thoroughbred racehorse
- Pyrogallol, when used as a photographic developing agent
- A chemistry prefix indicating a dimeric acid anhydride, e.g. pyrophosphoric acid
- Mineral Insulated Copper Clad cable, a type of fire resistant electrical cable commonly known as Pyro cable.