Prue may refer to:
People:
- Prue Acton (born 1943), Australian fashion designer
- Prue Lewarne, international news anchor
- Prue Watt (born 1987), Australian Paralympic swimmer
- Prue, a short form of Prudence (given name), including a list of people with this name
- Prue, a short form of Prunella (given name), including a list of people with this name
- Michael Prue (born 1948), Canadian politician
Other uses:
- Prue, Oklahoma, a town
- Prue, various gliders designed and built by Irving Prue