Proteolysis - Regulatiory Domains in Proteolysis

Regulatiory Domains in Proteolysis

Protease may have one or more regulatory domains -

  • Calcium-binding domain - e.g. prothrombin, factor IX, X, VII, protein C in blood clotting cascade, calpain.
  • Kringle domain - e.g. in prothrombin it keeps the protease inactive.

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