Protease Inhibitor (pharmacology) - Antiprotozoal Activity

Antiprotozoal Activity

Researchers are investigating the use of protease inhibitors developed for HIV treatment as anti-protozoals for use against malaria and gastrointestinal protozoal infections:

  • A combination of ritonavir and lopinavir was found to have some effectiveness against Giardia infection.
  • The drugs saquinavir, ritonavir, and lopinavir have been found to have anti-malarial properties.
  • A cysteine protease inhibitor drug was found to cure Chagas disease in mice.

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Famous quotes containing the word activity:

    A worm is as good a traveler as a grasshopper or a cricket, and a much wiser settler. With all their activity these do not hop away from drought nor forward to summer. We do not avoid evil by fleeing before it, but by rising above or diving below its plane; as the worm escapes drought and frost by boring a few inches deeper.
    Henry David Thoreau (1817–1862)