Prolactin-induced Protein

Prolactin-induced Protein

Identifiers Symbols PIP; GCDFP-15; GCDFP15; GPIP4 External IDs OMIM: 176720 MGI: 102696 HomoloGene: 1990 GeneCards: PIP Gene

Gene Ontology
Molecular function • actin binding
Cellular component • extracellular region
• apical plasma membrane
Biological process • biological_process
Sources: Amigo / QuickGO
RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 5304 18716 Ensembl ENSG00000159763 ENSMUSG00000058499 UniProt P12273 P02816 RefSeq (mRNA) NM_002652 NM_008843 RefSeq (protein) NP_002643 NP_032869 Location (UCSC) Chr 7:
142.83 – 142.84 Mb Chr 6:
41.85 – 41.85 Mb PubMed search

Prolactin-inducible protein also known as gross cystic disease fluid protein 15 (GCDFP-15), extra-parotid glycoprotein (EP-GP), gp17 seminal actin-binding protein (SABP) or BRST2 is a protein that in humans is encoded by the PIP gene. It is upregulated by prolactin and androgens and downregulated by estrogen.

Read more about Prolactin-induced Protein:  Function, Use As Marker and Significance in Disease

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