Role in Brain Damage
Studies as far back as 1987 show that female sex hormones have an effect on the recovery of traumatic brain injury.In these studies, it was first observed that pseudopregnant female rats had reduced edema after traumatic brain injury. Recent clinical trials have shown that among patients that have suffered moderate traumatic brain injury, those that have been treated with progesterone are more likely to have a better outcome than those who have not.
Previous studies have shown that progesterone supports the normal development of neurons in the brain, and that the hormone has a protective effect on damaged brain tissue. It has been observed in animal models that females have reduced susceptibility to traumatic brain injury and this protective effect has been hypothesized to be caused by increased circulating levels of estrogen and progesterone in females. A number of additional animal studies have confirmed that progesterone has neuroprotective effects when administered shortly after traumatic brain injury. Encouraging results have also been reported in human clinical trials.
Read more about this topic: Progesterone
Famous quotes containing the words role in, role, brain and/or damage:
“Always and everywhere children take an active role in the construction and acquisition of learning and understanding. To learn is a satisfying experience, but also, as the psychologist Nelson Goodman tells us, to understand is to experience desire, drama, and conquest.”
—Carolyn Edwards (20th century)
“American feminists have generally stressed the ways in which men and women should be equal and have therefore tried to put aside differences.... Social feminists [in Europe] ... believe that men and society at large should provide systematic support to women in recognition of their dual role as mothers and workers.”
—Sylvia Ann Hewitt (20th century)
“Thou hast no more brain than I have in mine elbows.”
—William Shakespeare (1564–1616)
“I learned early to understand that there is no such condition in human affairs as absolute truth. There is only truth as people see it, and truth, even in fact, may be kaleidoscopic in its variety. The damage such perception did to me I have felt ever since ... I could never belong entirely to one side of any question.”
—Pearl S. Buck (1892–1973)