Avi Kremer ALS Treatment Prize
In October 2008, Prize4Life launched a $1M award for a therapy that extends the life of ALS mice by 25%. Efficacy in animal models is a critical scientific and regulatory hurdle for the development of new drugs. The U.S. Food and Drug Administration (FDA) requires that all new drugs being developed (for any use in humans) be thoroughly tested in animal models before they can be approved for clinical trials in people. In addition, pharmaceutical and biotechnology companies use animal models to help them determine what potential therapeutics to invest time and resources in. Furthermore, no compound tested in ALS mouse models under rigorous experimental conditions has demonstrated the ability to reliably extend lifespan in these animals by even 10%.
Read more about this topic: Prize4Life
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