Primary sclerosing cholangitis (PSC) is a chronic liver disease caused by progressive inflammation and scarring of the bile ducts of the liver. The inflammation impedes the flow of bile to the gut, which can ultimately lead to liver cirrhosis, liver failure and liver cancer. The underlying cause of the inflammation is believed to be autoimmunity; and more than 80% of those with PSC have ulcerative colitis. The definitive treatment is liver transplantation.
Read more about Primary Sclerosing Cholangitis: Signs and Symptoms, Diagnosis, Etiology, Pathophysiology, Epidemiology, Related Diseases, Therapy, Prognosis
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