Prognosis
The age of onset is often in puberty. Of the described cases, as high as 80% of the affected individuals was suffering from the disease prior to the age of 18. However, Latos-Bielenska et al. stated that this percentage should be lower, because also another form of osteoarthropathy – familial idiopathic osteoarthropathy (FIO) - was taken into account in this analysis.
PDP usually progresses for 5 to 20 years, until it becomes stable. Life expectancy may be normal, despite patients getting many functional and cosmetic complications, including restricted motion, neurologic manifestations and leonine facies.
Read more about this topic: Primary Hypertrophic Osteoathropathy