Popo may refer to:
As a given name or surname:
- Popo Molefe (born 1952), South African politician and former Premier of the North West Province
- Hira Te Popo (died 1889), New Zealand tribal leader
- Sundar Popo (1943-2000), musician from Trinidad and Tobago
- Tosan Popo (born 1992), English footballer
As a nickname:
- Ching-Po Paul Chiang, also known as Po-po Chiang, symphony orchestra conductor, producer and chamber musician
- Acelino Freitas (born 1975), Brazilian boxer known as Popó
- Adilson Ferreira de Souza (born 1978), Brazilian footballer known as Popó
- Adolfo Moyano Burgos (born 1988), Spanish footballer
- Ivan Krstanović (born 1983), Croatian footballer
In entertainment:
- Popo (album), a 1951 jazz album by Shorty Rogers and Art Pepper
- Mr. Popo, a character in the manga and anime series Dragon Ball
- Popo, a character in the Japanese anime series Kaiba
- Popo, a player-controlled character in the Nintendo video game Ice Climber
Other uses:
- Popocatépetl, an active volcano in Mexico also called El Popo
- Gen language, also called Popo, spoken in Togo
- Phla language, also known as Popo, spoken in Benin and Togo
- Feng Po Po or Popo, Chinese goddess of the wind
- Plain Old PHP Object (similar to POJO in Java)
- Po-po, slang for a police officer