Properties
PPG has many properties in common with polyethylene glycol. The polymer is a liquid at room temperature. Solubility in water decreases rapidly with increasing molar mass. Secondary hydroxyl groups in PPG are less reactive than primary hydroxyl groups in polyethylene glycol. PPG is less toxic than PEG, so biotechnologicals are now produced in PPG.
(copied from IPCS Chemical Safety Information from Intergovernmental Organizations from www.inchem.org: Polypropylene glycol: Hazardous characteristics:)
Combustible and in the form of vapour explosive when exposed to heat or flame. When heated to decomposition it produces acrid and irritating fumes (Sax, 1989).
The toxicity of polypropylene glycol is mainly due to the parent compound and not to its metabolites. Polypropylene glycol has an irritatant effect on direct contact with eyes, mucous membranes and possibly after prolonged contact with skin.
Propylene glycol causes CNS depression similar to that caused by ethanol but it is only one-third as potent. Cardiotoxic effects include arrhythmias and cardiac arrest. Renal and hepatic damage has been reported (Seidenfeld & Hanzlik, 1932).
Read more about this topic: Polypropylene Glycol
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