Polyarteritis Nodosa - Treatment and Prognosis

Treatment and Prognosis

Treatment involves medications to suppress the immune system, including high-dose prednisone and cyclophosphamide. In single cases methotrexate may be also helpful . Therapy results in remissions or cures in 90% of cases. Untreated, the disease is fatal in most cases. The most serious associated conditions generally involve the kidneys and gastrointestinal tract. A fatal course usually involves gastrointestinal hemorrhage, infection, myocardial infarction and/or renal failure.

In case of remission, approximately 60% experience relapse within five years. In cases caused by hepatitis B virus, however, recurrence rate is only approximately 6%.

Read more about this topic:  Polyarteritis Nodosa

Famous quotes containing the words treatment and and/or treatment:

    James’s great gift, of course, was his ability to tell a plot in shimmering detail with such delicacy of treatment and such fine aloofness—that is, reluctance to engage in any direct grappling with what, in the play or story, had actually “taken place”Mthat his listeners often did not, in the end, know what had, to put it in another way, “gone on.”
    James Thurber (1894–1961)

    [17th-century] Puritans were the first modern parents. Like many of us, they looked on their treatment of children as a test of their own self-control. Their goal was not to simply to ensure the child’s duty to the family, but to help him or her make personal, individual commitments. They were the first authors to state that children must obey God rather than parents, in case of a clear conflict.
    C. John Sommerville (20th century)