PNS may refer to:
- Peripheral nerve stimulation (of the occipital nerves)
- Paraneoplastic Neurological Syndromes
- Parasympathetic nervous system
- Pakistan Naval Service/Submarine
- Peripheral nervous system
- Pensacola International Airport (IATA airport code)
- Pensacola (Amtrak station), (Amtrak station code)
- PNG Stereo, a 3D image format
- Portsmouth Naval Shipyard, United States
- Perceptual noise substitution, an audio encoding technique
- Professional network service, a networking platform used for professional connections
- Proof-number search, an algorithm for searching game trees
- Planetary Nebulae Spectrograph, a single purpose instrument on the William Herschel Telescope