In molecular biology the PLAT domain is protein domain that is found in a variety of membrane or lipid associated proteins. It is called the PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology) domain. The known structure of pancreatic lipase shows this domain binds to procolipase Pfam PF01114, which mediates membrane association.
This domain is found in a variety of membrane or lipid associated proteins. It forms a beta-sandwich composed of two sheets of four strands each.
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Famous quotes containing the word domain:
“You are the harvest and not the reaper
And of your domain another is the keeper.”
—John Ashbery (b. 1927)