Pipi may refer to:
- Plebidonax deltoides, an edible clam known as pipi in parts of Australia
- Paphies australis, a mollusc endemic to New Zealand
- Pipi A, a High Priest of Ptah during the Ancient Egyptian 21st Dynasty
- Neterkheperre Meryptah called Pipi II, another 21st Dynasty High Priest of Ptah
- Pipi, vocalist of the Ska band Ska-P
- A transcription (ΠΙΠΙ) into Greek of the Tetragrammaton
- A slang word for urine in a number of European languages