PIP5K1C

PIP5K1C

Identifiers Symbols PIP5K1C; LCCS3; PIP5K-GAMMA; PIP5Kgamma; PIPKIg_v4 External IDs OMIM: 606102 MGI: 1298224 HomoloGene: 69032 GeneCards: PIP5K1C Gene EC number 2.7.1.68

Gene Ontology
Molecular function ATP binding
1-phosphatidylinositol-4-phosphate 5-kinase activity
Cellular component phagocytic cup
uropod
nucleus
cytosol
focal adhesion
endomembrane system
ruffle membrane
Biological process phospholipid metabolic process
phosphatidylinositol biosynthetic process
phagocytosis
axon guidance
synaptic vesicle exocytosis
cell-cell adhesion
actin cytoskeleton organization
neutrophil chemotaxis
adherens junction assembly
small molecule metabolic process
synaptic vesicle endocytosis
clathrin-mediated endocytosis
Sources: Amigo / QuickGO
RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 23396 18717 Ensembl ENSG00000186111 ENSMUSG00000034902 UniProt O60331 O70161 RefSeq (mRNA) NM_001195733 NM_001146687 RefSeq (protein) NP_001182662 NP_001140159 Location (UCSC) Chr 19:
3.63 – 3.7 Mb Chr 10:
81.29 – 81.32 Mb PubMed search

Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma is an enzyme that in humans is encoded by the PIP5K1C gene.

This gene encodes a member of the type I phosphatidylinositol-4-phosphate 5-kinase family of enzymes. A similar protein in mice is found in synapses and focal adhesion plaques, and binds the FERM domain of talin through its C-terminus.

Read more about PIP5K1C:  Model Organisms