Pioneer axon is the classification given to axons that are the first grow in a particular region. They originate from pioneer neurons, and have the main function of laying down the initial growing path that subsequent growing axons, dubbed follower axons, from other neurons will eventually follow.
Several theories relating to the structure and function of pioneer axons are currently being explored. The first theory is that pioneer axons are specialized structures, and that they play a crucial role in guiding follower axons. The second is that pioneer axons are no different from follower axons, and that they play no role in guiding follower axons.
Anatomically, there are no differences between pioneer and follower axons, although there are morphological differences. The mechanisms of pioneer axons and their role in axon guidance is currently being explored. In addition, many studies are being conducted in model organisms, such grasshoppers, zebrafish, and fruit flies to study the effects of manipulations of pioneer axons on neuronal development.
Read more about Pioneer Axon: History, Mechanisms of Growth, Chemotactic Influences, Anatomy, Role of Pioneer Axons in Neuronal Development, See Also
Famous quotes containing the word pioneer:
“America is the civilization of people engaged in transforming themselves. In the past, the stars of the performance were the pioneer and the immigrant. Today, it is youth and the Black.”
—Harold Rosenberg (1906–1978)