Pierre DuPont may refer to:
- Pierre Dupont, French song-writer
- Pierre DuPont (carpet maker) founder of French carpet making (c. 1600)
- Pierre Dupont de l'Étang, French General
- Pierre S. du Pont (1870–1954), Du Pont Company and General Motors executive
- Pierre S. du Pont IV (born 1935), American lawyer and politician, Governor of Delaware
- Pierre Samuel du Pont de Nemours (1739–1817), entrepreneur
- Pierre Dupont (Tomb Raider), a character from the Tomb Raider video game series