Sub-types
Phosphatases can be subdivided based upon their substrate specificity.
| Class | Example | Substrate | Reference |
|---|---|---|---|
| Tyrosine-specific phosphatases | PTP1B | Phospho-Tyrosine | |
| Serine/Threonine specific phosphatases | PP2C (PPP2CA) | Phospho-Serine/Threonine | |
| Dual Specificity Phosphatases | VHR, DUSP1 to DUSP28 | Phospho-Tyrosine/Serine/Threonine | |
| Histidine Phosphatase | PHP | Phospho-Histidine | |
| Lipid Phosphatase | PTEN | Phosphatidyl-Inositol-3,4,5-Triphosphate |
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