Phenolphthalein - Physiology

Physiology

Despite concerns of its carcinogenicity, the use of phenolphthalein as a laxative is unlikely to cause ovarian cancer.

Phenolphthalein has been found to inhibit human cellular calcium influx via store-operated calcium entry (SOCE) by inhibiting thrombin and thapsigargin, two activators of SOCE that increase intracellular free calcium.

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