Location and Appearance
Peyer's patches are observable as elongated thickenings of the intestinal epithelium measuring a few centimeters in length. About 30 are found in humans. Microscopically, Peyer’s patches appear as oval or round lymphoid follicles (similar to lymph nodes) located in the lamina propria layer of the mucosa and extending into the submucosa of the ileum.
In adults, B lymphocytes are seen to predominate in the follicles' germinal centers. T lymphocytes are found in the zones between follicles.
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