Peter Hotez - Neglected Tropical Disease (NTD) Vaccine Research and Development ('the Antipoverty Vaccines')

Neglected Tropical Disease (NTD) Vaccine Research and Development ('the Antipoverty Vaccines')

As President of the Sabin Vaccine Institute and Director of its product development partnership (PDP) Hotez leads an international team of scientists working to develop vaccines to combat hookworm infection, schistosomiasis, and other infectious and neglected diseases, including Chagas disease, leishmaniasis, and SARS. These diseases are the most common infections of the world’s poorest people.

Together with Philip K. Russell, Hotez founded the Human Hookworm Vaccine Initiative (HHVI) in 1999, the first initiative of the Sabin Vaccine Institute PDP. Innovations developed by Sabin Vaccine Development—funded by the Bill & Melinda Gates Foundation, the Dutch Ministry of Foreign Affairs and others—are sometimes referred to as “antipoverty vaccines” because of their impact on both global health and economic development. Antipoverty vaccines against hookworm are now in clinical trials in Brazil, while a new vaccine for schistosomiasis will soon undergo clinical testing. The vaccines for Chagas disease, leishmaniasis, and SARS are at an earlier stage of development, with support from the NIAID, NIH, Carlos Slim Health Institute, Southwest Electric Energy Medical Research Institute, and key individuals.

The Sabin Vaccine Institute PDP develops new antipoverty vaccines jointly with innovative developing countries, such as Brazil and Mexico, with aspirations to extend these activities to the Middle East and Asia. Hotez writes extensively about vaccine diplomacy, i.e., the opportunity of using vaccines as instruments of foreign policy and to promote global peace, especially among poor countries seeking nuclear weapons technology..


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