Periwinkle may refer to:
In fauna:
- Periwinkle, a common name for a number of gastropod molluscs in the family Littorinidae
- Common periwinkle (Littorina littorea)
- Blue periwinkle (Nodilittorina unifasciata)
- Rough periwinkle (Littorina saxatilis)
- Periwinkle, a regional name for the caddisfly larva
In flora:
- Catharanthus or Madagascar periwinkles
- Catharanthus roseus or rosy periwinkle
- Vinca or European periwinkles
- Vinca major or greater periwinkle
- Vinca minor or lesser periwinkle
- Vinca herbacea or herbaceous periwinkle
In other uses:
- Periwinkle (color), a pale shade of blue
- Periwinkle (film), a 1917 silent film by James Kirkwood
- USS Periwinkle (1864), a steamer procured by the Union Navy during the American Civil War
- Periwinkle, a character in Blue's Clues
- Periwinkle, a character in The Bellflower Bunnies
- Periwinkle, a character in Tinker Bell and the Secret of the Wings
- Periwinkle, the main character in Patricia A. McKillip's book, The Changeling Sea