Peripheral Stem Cell Transplantation
Peripheral blood stem cell transplantation (PBSCT), also called peripheral stem cell support, is a method of replacing blood-forming stem cells destroyed, for example, by cancer treatment. PBSCT is now a much more common procedure than its bone marrow harvest equivalent, this is in-part due to the ease and less invasive nature of the procedure. Studies suggest, that PBSCT has a better outcomes in terms of the number of hematopoietic stem cell (CD34+ cells) yield.
Immature blood cells hematopoietic stem cells in the circulating blood that are similar to those in the bone marrow are collected by apheresis from a potential donor (PBSC collection). The product is then administered intravenously to the patient after treatment. The administered hematopoietic stem cells then migrate to the recipients bone marrow, a process known as stem cell homing, where the transplanted cells override the previous bone marrow. This allows the bone marrow to recover, proliferate and continue producing healthy blood cells.
The transplantation may be autologous (an individual's own blood cells saved earlier), allogeneic (blood cells donated by someone else with matching HLA), or syngeneic (blood cells donated by an identical twin). The procedure typically lasts for 4–6 hours, depending on the donors total blood volume.
Read more about Peripheral Stem Cell Transplantation: Complications
Other articles related to "stem, cell, cells, stems":
... Bone Marrow and Stem Cell Transplant Therapies Several trials are underway to continue to improve the effectiveness and reduce the risks of bone marrow and stem cell ... America, or China that would be happy to take your money and have you believe stem cell infusions will "cure" MLD ... Institute are testing a novel approach combining gene therapy with a stem cell transplant ...
... A stem cell possesses two properties Self-renewal, which is the ability to go through numerous cycles of cell division while still maintaining its ... which is the ability to generate progeny of several distinct cell types, (for example glial cells and neurons) as opposed to unipotency, which is the term for cells that ... and believe that unipotent self-renewing stem cells can exist ...
... category in Kulung and are formed by the addition of an affix to a verb stem ... pronominalisation, in which paradigmatic stem alternation is found ... Depending on the number of verbal stems and their position in the verbal paradigm, every verb in Kulung belongs to a certain conjugation type ...
... Currently, she is conducting the first human clinical trial of a stem cell therapy for ALS ... Michigan citizens on the importance of stem cell research in the study and treatment of disease ... a constitutional amendment lifting restrictions on stem cell research in the state ...
... To the left and behind the Şehzade Türbe is the türbe of Grand Vizier Rüstem Pasha, also by Sinan ... Rüstem Pasha was the son-in-law of Suleiman the Magnificent ... As at the Rüstem Pasha Mosque, an overwhelming quantity of Iznik tiles was used ...
Famous quotes containing the words cell, peripheral and/or stem:
“Let man consider what he is in comparison with all existence; let him regard himself as lost in this remote corner of nature; and from the little cell in which he finds himself lodged, I mean the universe, let him estimate at their true value the earth, kingdoms, cities, and himself. What is a man in the infinite?”
—Blaise Pascal (1623–1662)
“If we are to change our world view, images have to change. The artist now has a very important job to do. He’s not a little peripheral figure entertaining rich people, he’s really needed.”
—David Hockney (b. 1937)
“Bite down
on the bitter stem of your nectared
rose, you know
the dreamy stench of death and fling
magenta shawls delicately
about your brown shoulders laughing.”
—Denise Levertov (b. 1923)