Measurement Using Nuclear Medicine Methods
Perfusion of various tissues can be readily measured in vivo with nuclear medicine methods, mainly positron emission tomography (PET) and single photon emission computed tomography (SPECT). Various radiopharmaceuticals targeted at specific organs are available, some of the most common being
- 99mTc labelled HMPAO and ECD for brain perfusion (rCBF) studied with SPECT
- 99mTc labelled Tetrofosmin and Sestamibi for Myocardial_perfusion_imaging with SPECT
- 133Xe-gas for absolute quantification of brain perfusion (rCBF) with SPECT
- 15O-labeled water for brain perfusion (rCBF) with PET (absolute quantification possible when measuring arterial radioactivity concentration)
- 82Rb-chloride for measuring myocardial perfusion with PET (absolute quantification is possible)
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