Penryn is a Cornish word meaning 'headland' that may refer to:
- Penryn, Cornwall, United Kingdom, a town of about 7,000 on the River Penryn
- Penryn (UK Parliament constituency) a former constituency based on Penryn, Cornwall
- Penryn, California, in the United States, a town of about 2,000 and home to a granite quarry
- Penryn (microprocessor), code name for a CPU from Intel, used in Core 2 Duo