Drug Resistance
Treatment with anti-fungal drugs often results in the appearance of resistant strains of fungi. Various mechanisms leading to resistance have been described. For example, a number of resistant clinical isolates overexpress genes encoding drug efflux pumps. Recent advances in molecular biology have allowed the study of the phenomenon of multi-drug resistance on a genome-wide scale. DNA micro-arrays are being used to study the expression profiling of pathogenic fungi and proteomics is aiding research in the development of resistance to various anti-fungal drugs.
Read more about this topic: Pathogenic Fungi
Famous quotes containing the words drug and/or resistance:
“While man can still his body keep
Wine or love drug him to sleep,
Waking he thanks the Lord that he
Has body and its stupidity....”
—William Butler Yeats (1865–1939)
“High treason, when it is resistance to tyranny here below, has its origin in, and is first committed by, the power that makes and forever re-creates man.”
—Henry David Thoreau (1817–1862)