PASK

Identifiers Symbols PASK; PASKIN; STK37 External IDs OMIM: 607505 MGI: 2155936 HomoloGene: 9038 ChEMBL: 6054 GeneCards: PASK Gene EC number 2.7.11.1

Gene Ontology
Molecular function	• protein serine/threonine kinase activity • signal transducer activity • protein binding • ATP binding • phosphatidylinositol binding
Cellular component	• nucleus • cytoplasm • Golgi apparatus
Biological process	• protein phosphorylation • regulation of respiratory gaseous exchange • negative regulation of glycogen biosynthetic process • positive regulation of translation • protein autophosphorylation • regulation of glucagon secretion • regulation of energy homeostasis
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 23178 269224 Ensembl ENSG00000115687 ENSMUSG00000026274 UniProt Q96RG2 Q8CEE6 RefSeq (mRNA) NM_001252119 NM_080850 RefSeq (protein) NP_001239048 NP_543126 Location (UCSC) Chr 2:
242.05 – 242.09 Mb Chr 1:
93.31 – 93.34 Mb PubMed search

PAS domain-containing serine/threonine-protein kinase is an enzyme that in humans is encoded by the PASK gene.

PAS domains regulate the function of many intracellular signaling pathways in response to both extrinsic and intrinsic stimuli. PASK is an evolutionarily conserved protein present in yeast, flies, and mammals.