Lesions
Unilateral lesions of the PPRF produce characteristic findings:
- Loss of horizontal saccades directed towards the side of the lesion, no matter the current position of gaze
- Contralateral gaze deviation (acute lesions, such as early stroke, only)
- Gaze-evoked lateral nystagmus on looking away from the side of the lesion
Bilateral lesions produce horizontal gaze palsy and slowing of vertical saccades
Read more about this topic: Paramedian Pontine Reticular Formation
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“Not that success, for him, is sure, infallible.
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His lesions are legion.
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—Gwendolyn Brooks (b. 1917)