Pamela may refer to:
- Pamela, or Virtue Rewarded, a novel written by Samuel Richardson in 1740
- Pamela (name), a given name and, rarely, a surname
- Pamela (singer), Canadian singer who has recorded with Akon
- MSC Pamela, a container ship launched in 2005
- Pamela (butterfly), a butterfly genus
- Species of butterfly Perrhybris pamela
- Pamela, answering machine software functioning with the software Skype
- Super Typhoon Pamela, a typhoon in 1976
- "Pamela Pamela", a song recorded by Wayne Fontana that reached #11 in the UK Singles Chart in 1967
- "Pamela" (song), a 1988 hit song for the band Toto
- "Pamella", a song by Remmy Ongala from the album Songs For the Poor Man
In acronyms:
- PAMELA Project, Process for Advanced Management of End of-Life-Aircraft
- Payload for Antimatter Matter Exploration and Light-nuclei Astrophysics, astrophysical satellite module
- Pedestrian Accessibility and Movement Environment Laboratory, artificial pavement at a research center at University College London