Palmitoleic Acid - Potential Biological Effects

Potential Biological Effects

In an analysis of numerous fatty acids, palmitoleate was shown to possibly influence fatty liver deposition/production, insulin action, palmitate, and fatty acid synthase, leading to proposal of a new term, "lipokine" having hormone-like effects.

As one such effect may include improved insulin sensitivity, palmitoleic acid (C16:1 n-7) was shown in diabetic mice to attenuate hyperglycemia and hypertriglyceridemia by increasing insulin sensitivity, in part owing to suppression of pro-inflammatory gene expressions and improving hepatic lipid metabolism.

Other preliminary research indicated that palmitoleic acid could have a role as a signaling molecule affecting body weight, a finding consistent with previous observations that palmitoleic acid, among other fatty acids available in the diet, may be used by enzymes affecting fat oxidation. Consequently, oil types manufactured with high palmitoleic acid content may have a role in addressing obesity.

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