Units
Much like pyruvate dehydrogenase complex (PDC), this enzyme forms a complex composed of three components:
| Unit | EC number | Name | Gene | Coenzyme |
| E1 | EC 1.2.4.2 | oxoglutarate dehydrogenase | OGDH | thiamine pyrophosphate |
| E2 | EC 2.3.1.61 | dihydrolipoyl succinyltransferase | DLST | lipoic acid |
| E3 | EC 1.8.1.4 | dihydrolipoyl dehydrogenase | DLD | FAD |
In fact, three classes of these multienzyme complexes have been characterized, one specific for pyruvate, a second specific for 2-oxoglutarate, and a third specific for branched-chain α-keto acids.
Read more about this topic: Oxoglutarate Dehydrogenase Complex
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