Families
A nomenclature system has been devised for the olfactory receptor family and is the basis for the official Human Genome Project (HUGO) symbols for the genes that encode these receptors. The names of individual olfactory receptor family members are in the format "ORnXm" where:
- OR is the root name (Olfactory Receptor superfamily)
- n = an integer representing a family (e.g., 1-56) whose members have greater than 40% sequence identity,
- X = a single letter (A, B, C, ...) denoting a subfamily (>60% sequence identity), and
- m = an integer representing an individual family member (isoform).
For example OR1A1 is the first isoform of subfamily A of olfactory receptor family 1.
Members belonging to the same subfamily of olfactory receptors (>60% sequence identity) are likely to recognize structurally similar odorant molecules.
Two major classes of olfactory receptors have been identified in humans:
- class I (fish-like receptors) OR families 51-56
- class II (tetrapod specific receptors) OR families 1-13
Read more about this topic: Olfactory Receptor
Famous quotes containing the word families:
“Family jokes, though rightly cursed by strangers, are the bond that keeps most families alive.”
—Stella Benson (1892–1933)
“For those parents from lower-class and minority communities ... [who] have had minimal experience in negotiating dominant, external institutions or have had negative and hostile contact with social service agencies, their initial approaches to the school are often overwhelming and difficult. Not only does the school feel like an alien environment with incomprehensible norms and structures, but the families often do not feel entitled to make demands or force disagreements.”
—Sara Lawrence Lightfoot (20th century)
“Take two kids in competition for their parents’ love and attention. Add to that the envy that one child feels for the accomplishments of the other; the resentment that each child feels for the privileges of the other; the personal frustrations that they don’t dare let out on anyone else but a brother or sister, and it’s not hard to understand why in families across the land, the sibling relationship contains enough emotional dynamite to set off rounds of daily explosions.”
—Adele Faber (20th century)