Miscellaneous
- offering circular in finance, "the OC" for a bond offering
- The O.C., an American television show set in Orange County, California
- Obsessive-compulsive disorder (more common written form: OCD)
- Oleoresin Capsaicin or Oleoresin Capsicum, the active ingredient in pepper spray and OC gas
- OC Spray, also known as Pepper spray
- OC Transpo, a public transit operator in Ottawa, Ontario, Canada
- Only Connect, a British television programme
- Orange County, a 2002 comedy film
- Organized crime
- openCanvas, an art program
- Open cluster in astronomy
- Operation Completion
- Oral contraceptive, usually referring to the combined oral contraceptive pill
- Oregon Crusaders Drum and Bugle Corps, a Drum Corps International group commonly abbreviated as "OC"
- Original character, in fan fiction
- Original content, in Internet abbreviation
- Oxi Clean, a cleaning product
- On Center, the measurement of spacing for studs, rafters, and joists in a building from the center of one member to the center of the next.
- OxyContin
- PGA Express IATA airline designator
- Outrigger Canoe
- Opus clavicembalisticum, a piece for piano by Kaikhosru Shapurji Sorabji
- "Oc", an abbreviation for "Ocarina"
- Vin de Pays D'Oc, where "Oc" is the short form for Languedoc-Roussillon.
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