Obra may refer to:
- Obra (art) - a masterpiece, or artful works
- Obra, Uttar Pradesh - a town in the Indian state of Uttar Pradesh
- Obra, Bihar - a town in Bihar
- Obra (river) - a river in west Poland
- Obra, Greater Poland Voivodeship (west-central Poland)
- Oregon Bicycle Racing Association
- Obra (TV series) - a drama anthology airing on GMA Network
- Omnibus Budget Reconciliation Act of 1990 - a United States statute signed by President George H.W. Bush
- Omnibus Budget Reconciliation Act of 1993 - a United States statute signed by President Bill Clinton