Reaction Mechanism
Conjugate addition is the vinylogous counterpart of direct nucleophilic addition. A nucleophile reacts with a α,β-unsaturated carbonyl compound in the β position. The negative charge carried by the nucleophile is now delocalized in the alkoxide anion and the α carbon carbanion by resonance. Protonation leads through Keto-enol tautomerism to the saturated carbonyl compound. In vicinal difunctionalization the proton is replaced by another electrophile.
Read more about this topic: Nucleophilic Conjugate Addition
Famous quotes containing the words reaction and/or mechanism:
“The excessive increase of anything often causes a reaction in the opposite direction.”
—Plato (c. 427347 B.C.)
“Ive never known a Philadelphian who wasnt a downright character; possibly a defense mechanism resulting from the dullness of their native habitat.”
—Anita Loos (18881981)