NUB1

NUB1

Identifiers Symbols NUB1; BS4; NUB1L; NYREN18 External IDs OMIM: 607981 MGI: 1889001 HomoloGene: 41108 GeneCards: NUB1 Gene

Gene Ontology
Molecular function	• protein binding
Cellular component	• nucleus
Biological process	• ubiquitin-dependent protein catabolic process • protein ubiquitination • positive regulation of proteasomal ubiquitin-dependent protein catabolic process • response to interferon-gamma • response to tumor necrosis factor
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 51667 53312 Ensembl ENSG00000013374 ENSMUSG00000028954 UniProt Q9Y5A7 P54729 RefSeq (mRNA) NM_001243351 NM_016736 RefSeq (protein) NP_001230280 NP_058016 Location (UCSC) Chr 7:
151.04 – 151.08 Mb Chr 5:
24.69 – 24.71 Mb PubMed search

NEDD8 ultimate buster 1 is a protein that in humans is encoded by the NUB1 gene.

NUB1 interacts with and negatively regulates NEDD8 (MIM 603171), a ubiquitin-like protein that covalently conjugates to cullin (see MIM 603134) family members.