The three character combination NRS may refer to:
- JANET NRS Janet Name Registration Scheme
- NRS social grade
- NRS process used for sugar thin-juice decalification in beet sugar factories
- NRS National Retail Systems Inc., Global Logistics and Trucking
- Non-Rocket Spacelaunch in spaceflight
- The National Runaway Switchboard, a national US hotline for youth in crisis.
- Nevada Revised Statutes Nevada laws
- Nuclear receptor signaling, in biology, the signaling on or off of genes (or parts of genes) in a cell that affect biological mechanisms (metabolism, development, &c).
- NRs. is the unofficial short code for the Nepalese Rupee