NPG may refer to:
- Related to Prince:
- The New Power Generation
- NPG Records
- NPG Music Club
- Several National Portrait Galleries:
- National Portrait Gallery (Australia)
- National Portrait Gallery (London)
- National Portrait Gallery (United States)
- Scottish National Portrait Gallery
- Nature Publishing Group, a publisher based in London
- Negative Population Growth, an organization in the United States
- Neopentyl glycol
- Non Processor (DMA) Grant, part of Unibus, an early computer bus
- Nevada Proving Grounds, a former name of the Nevada Test Site
- The Nederlands Padvindsters Gilde (Dutch Girl-pathfinders Guild), one of the Scouting organisations that evolved into Scouting Nederland
- News-Press & Gazette Company, a United States print, cable & broadcast media group
- Network Participating Group, a functional group of Link 16 participants